Both Marvel and Sony have allegedly talked about using far less romance in future Spider-Man films. MJ is largely seen as "the love interest" so chances are her role will be minimal in future films (if she's present at all).
Marvel has especially been pushing for a younger single Spider-man. Just look at MJ's role in the Ultimate show. Yes, I know that film and animation are completely seperate divisions, but it still fits their current agenda. I can't see them promoting a character and a relationship that they've been trying to move away from (with the exception of Renew Your Vows, but of course, how that plays out remains to be seen).
My gut tells me that they'll approach MJ with the same mentality of "her story has already been told".
Always loved that early Beatnik-Go Goish look on Watson.
There were people at Sony who suggested Kraven's Last Hunt as a potential story for adaptation, and they name dropped MJ quite heavily.
Now, what happens if Marvel gets their hands on the Spider-Man film rights? An interesting question. They still invoke her quite frequently, and the movies do put a focus on the older characters and relationships. And after the ASM films, I doubt that we'll see Gwen again anytime soon in a film. (Outside of a cameo if that animated film from the directors of The Lego Movie happens.) Her story has been told. (As has Richard Parker's, thankfully. I hate that Richard Parker stuff.)I might suggest looking at what is widely thought to be the most beloved Spider-Man storyline of all time – “Kraven’s Last Hunt” – which ran across ‘Amazing Spider-Man’ #293-294, ‘Spectacular Spider-Man’ #131-132, and ‘Web of Spider-Man’ #31-32. (In fact, Comic Book Resources polled their readers in 2012, and this storyline was voted as the single greatest Spider-Man storyline of all time.)
In it, Kraven the Hunter tracks down Spider-Man, shoots him repeatedly, and leaves him for dead, buried underground. He then dons a Spider-Man costume and savagely starts attacking criminals.
What makes this story resonate with fans is that it proves it takes more than just the costume to become “Spider-Man.” No matter what he’s wearing, or what predicament he’s facing, Peter Parker is sensitive, passionate, and connected to those he’s interacting with in a very powerful way. It’s not Peter’s powers that make him special – Kraven, and every other superhuman in the Marvel Universe, all have powers. Peter is special because of his values, because of what drives him, because of the lessons he’s learned from Uncle Ben’s death, and because of his love for Mary Jane. I’ve pasted a few pivotal pages from this book so you can see just how intense this storyline is.
We also get to see how Mary Jane deals with Peter’s disappearance, and how she would react if Peter ever died in action.
Marvel certainly got some attention with "Renew Your Vows" even if I don't think much of it beyond an AU story.Oh, she'll be back in the spotlight. It might not happen as soon we'd like, but it'll most definitely happen.