A comment on Superior Foes of Spider-Man got me thinking. What is your favorite Spider-Man spinoff? For the purpose of this thread, a spinoff would be when a character introduced in the Spider-Man books became the lead in a solo title.
I'm not counting Punisher, because that choice might be too dominant. Spider-Man Loves Mary Jane strikes me as a reimagining rather than a spinoff. The Jessica Drew Spider-Woman was not introduced in the pages of Spider-Man, so I wouldn't count her. Arana was tied to JMS's Amazing Spider-Man run, so she counts. And Spider-Man 2099 dealt with the legacy of the Marvel Universe, so I'm counting it as a spinoff.
For the purpose of this thread, Venom is two choices depending on whether you preferred the solo adventures of Eddie Brock or Flash Thompson. Morbius can refer to the 1990s series, the Marvel Now! book or his solo stories in the 1970s.